Fennegens, Inc.

Metabolic medicine, engineered for duration and disease modification

Fennegens is building a preclinical pipeline of long-acting GLP-1, multi-target and fusion-protein therapeutics for type 2 diabetes, obesity and NASH — designed so that glucose control, weight and tissue repair are addressed by a single, patient-friendly regimen.

5Pipeline assets
4Discovery platforms
4Modality classes
8 yrsMetabolic R&D
Why Fennegens

A pipeline built around three hard problems

Metabolic therapy today still leaves most patients short of durable control. Our programs attack the three bottlenecks that limit outcomes: dosing burden, single-mechanism ceilings, and the absence of regenerative options.

Duration by design

Weekly and monthly dosing formats are engineered into the molecule itself — not bolted on through pumps or high-volume formulations.

One regimen, several mechanisms

Multi-target agonists and dual-mechanism fusion proteins pair complementary metabolic signalling pathways to act on glucose, weight and muscle together. Target combinations are disclosed under a confidentiality agreement.

Regeneration, not only substitution

A first-in-class, regeneration-oriented peptide programme aimed at pancreatic β-cell regeneration — chemical class and molecular target are disclosed under a confidentiality agreement — with cure-oriented intent in early-onset diabetes.

Pipeline at a glance

Five assets across four modality classes

All programs are at the preclinical / candidate-selection stage. No product below has been approved by any regulatory authority.

AssetModalityTarget(s)Dosing intentLead indication(s)Stage
Fin2678Long-acting peptideUndisclosedWeeklyType 2 diabetes, obesityPCC / preclinical
Fin0311Regeneration-oriented peptide (first-in-class)UndisclosedWeeklyMild type 2 diabetes; paediatric diabetesPCC / preclinical
Fin529Multi-target peptideUndisclosedMonthlyType 2 diabetes, obesityPCC / preclinical
Fin608Long-acting fusion proteinUndisclosedLong-actingType 2 diabetes, weight managementPCC / preclinical
Fin611Dual-action long-acting fusion proteinUndisclosedLong-actingNASH, type 2 diabetes, obesity, metabolic syndromePCC / preclinical
Milestones

Development plan

Near term we are completing IND-enabling work and early clinical development; over the medium term the goal is to advance multiple programs into Phase II/III; longer term, commercial launch.

Near term

Complete IND filings and open first-in-human studies for our lead metabolic assets.

Medium term

Advance multiple programs into Phase II/III clinical development, with differentiated dosing formats.

Long term

Commercial-scale manufacturing, market access and partnering across major territories.

Partnering and collaboration

We welcome co-development, licensing and research collaboration across our platforms, and are glad to discuss how these programmes can be advanced with the right partners.